PE anti-human CD50 (ICAM-3) Antibody, CD50, A22041E,BioLegend,377117

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB241184849

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePE anti-human CD50 (ICAM-3) Antibody, CD50, A22041E
Cat. No.377117
HostMouse
RRIDAB_3720617 (BioLegend Cat. No. 377117)AB_3720617 (BioLegend Cat. No. 377118)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberA22041E
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD50
ImmunogenRecombinant Human ICAM3
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD50, also known as intercellular adhesion molecule 3 (ICAM-3), is a 120-140 kD type I membrane protein and member of the Ig superfamily. It is broadly expressed on leukocytes, endothelial cells, and Langerhans cells. CD50 provides costimulatory signals for T cells and regulates cell adhesion through interaction with LFA-1 (CD11a/CD18, αL/β2) integrin.

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