PE anti-human CD66 (CEACAM4/6) Antibody, CD66, W20030D,BioLegend,387704
Clone W20030D binds both CEACAM4 and CEACAM6.
Host
Rat
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB397032535

BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Specifications
Scientific Background
CEACAM4, also known as CGM7, belongs to the immunoglobulin superfamily, specifically the carcinoembryonic antigen (CEA)-like subfamily. It is an orphan receptor that serves a phagocytic function in human granulocytes.CD66c, also known as CEACAM6, is one of the splice variants of CD66. It is expressed on endothelial, epithelial cells, neutrophils, monocytes, and myeloma and cancer cells, such as B-cell acute lymphoblastic lymphomas. CD66 expression level can be induced on T cells, B cells, and CD16-negative NK cells. Like the other CD66 splice variants, CD66c is involved in cell adhesion and growth, neutrophil activation, and signaling. It plays a role in hemophilic and heterophilic adhesion.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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