PE anti-human CD73 Ecto-5-nucleotidase Antibody anti-CD73 - AD2,BioLegend,344003
Additional reported applications (for the relevant formats) include:immunofluorescence3.Clone AD2 has been noted to induce clustering and internalization of CD73in vivoand inhibit metastasis in a murine breast cancer xenograft model4.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB953889024
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NamePE anti-human CD73 Ecto-5-nucleotidase Antibody anti-CD73 - AD2
Cat. No.344003
HostMouse
RRIDAB_1877224 (BioLegend Cat. No. 344003)AB_2298698 (BioLegend Cat. No. 344004)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberAD2
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD73
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD73 is a 70 kD glycophosphatidylinositol (GPI)-linked 5'-nucleotidase, which is also known as ecto-5'-nucleotidase. It converts adenosine monophosphate (AMP) to adenosine. CD73 is expressed on subsets of T and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, and epithelial cells. It has been reported that CD73 costimulates T cell activation, and mediates adhesion of lymphocytes to follicular dendritic cells and endothelial cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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