PE anti-human DR3 TRAMP Antibody anti-DR3 - JD3,BioLegend,307106

Additional reported applications (for the relevant formats) include: The JD3 antibody is useful for immunofluorescent staining and flow cytometric analysis of DR3/TRAMP receptor expression. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 307106) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 307104) or biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB614984190

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePE anti-human DR3 TRAMP Antibody anti-DR3 - JD3
Cat. No.307106
HostMouse
RRIDAB_2240863 (BioLegend Cat. No. 307105)AB_2256350 (BioLegend Cat. No. 307106)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberJD3
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetDR3
Immunogenhuman DR3-Ig fusion protein
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

DR3 is also known as TNFRSF25, Apo-3, WSL-1, TRAMP, LARD, DDR3, and TR3. It is a member of the TNF receptor family expressed at low level by monocytes and granulocytes. Interaction of DR3 with its ligand (TWEAK), activates the NF-κB pathway and induces apoptosis.

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