PE anti-human HVCN1 Antibody, HVCN1, W23068A,BioLegend,377109

Host

Rat

Reactivity

Human

Application

ICFC - Quality tested

Platform ID

BAB399831191

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePE anti-human HVCN1 Antibody, HVCN1, W23068A
Cat. No.377109
HostRat
IsotypeRat IgG2a, κ
ReactivityHuman
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone NumberW23068A
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool).
TargetHVCN1
ImmunogenRecombinant human HVCN1
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Hydrogen voltage-gated channel 1 (HVCN1) is a voltage gated, proton-selective channel expressed in immune cells, spermatozoa, and upper respiratory tract epithelial cells. HVCN1 mediates proton conductance to prevent membrane depolarization and cytoplasmic acidification. In phagocytes, it is required for the oxidative burst that underlies microbial killing, and in B cells, it facilitates antibody production. HVCN1 can also regulate functions in other cells including spermatozoa.

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