PE anti-human IL-27Rα Antibody, IL-27Rα, W16093B,BioLegend,384603
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB516297789
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NamePE anti-human IL-27Rα Antibody, IL-27Rα, W16093B
Cat. No.384603
HostMouse
RRIDAB_2941562 (BioLegend Cat. No. 384603)AB_2941562 (BioLegend Cat. No. 384604)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberW16093B
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetIL-27Ralpha
ImmunogenHuman IL-27Rα transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
69 kD glycosylated transmembrane subunit of IL-27 receptor complex consisting of IL27Ra (WSX-1, TCCR) and gp130 (CD130). Expressed on T cells, monocytes, and neutrophils and aside from its effect on innate immunity, is involved in dampening the extent of Th1 immune response post infection. Activity levels of IFN-γand IL-17 producing T cells are regulated through this receptor which relays signal through Jak-STAT pathway.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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