PE anti-human IL-9 Antibody anti-IL-9 - MH9A4,BioLegend,507605

ELISA Capture2:The purified MH9A4 antibody is useful as the capture antibody in a human IL-9 sandwich ELISA assay, when used in conjunction with the biotinylated MH9D1 antibody as the detecting antibody.For human IL-9 neutralization assay, the LEAF™ purified MH9D1 antibody (Endotoxin <0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for neutralization of human IL-9 bioactivity.

Host

Mouse

Reactivity

Human

Application

ICFC - Quality tested

Platform ID

BAB753140372

BioLegend

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Contact

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Product Specifications
Scientific Background

Specifications

NamePE anti-human IL-9 Antibody anti-IL-9 - MH9A4
Cat. No.507605
HostMouse
RRIDAB_315486 (BioLegend Cat. No. 507604)AB_315485 (BioLegend Cat. No. 507603)AB_315487 (BioLegend Cat. No. 507605)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone NumberMH9A4
Concentrationµg sizes: 0.2 mg/mLtest sizes: lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetIL-9
ImmunogenBaculovirus-expressed, recombinant human IL-9
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Formulationtest sizes: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).µg size: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

IL-9 is a potent, T cell-derived, T cell growth factor which can also enhance mast cell activity and IL-3- or IL-4- dependent proliferation of bone marrow-derived mast cells. IL-9 synergizes with erythropoietin to promote erythroid colony formation. IL-9 has also been reported to protect human T cells from apoptosis induced by IL-2 withdrawal. IL-9 is upregulated in human eosinophils by TNF-α and IL1-β. IL-9 has been reported to downregulate the oxidative burst in activated human alveolar macropahges and induce TGF-β production. The MH9A4 antibody reacts with human IL-9. The MH9A4 antibody can neutralize the bioactivity of natural or recombinant IL-9.

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