PE anti-human IRF3 Antibody, IRF3, AR1,BioLegend,395904

Host

Mouse

Reactivity

Human

Application

ICFC -Quality tested

Platform ID

BAB580600702

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePE anti-human IRF3 Antibody, IRF3, AR1
Cat. No.395904
HostMouse
RRIDAB_2801066 (BioLegend Cat. No. 395903)AB_2801067 (BioLegend Cat. No. 395904)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationICFC -Quality tested
ClonalityMonoclonal
Clone NumberAR1
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetIRF3
ImmunogenRecombinant human IRF-3 protein (entire protein)
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

IRF-3 is a roughly 50 kD member of the interferon regulatory transcription factor (IRF) family. Along with other members of the IRF family IRF-3 plays a key role in the innate immune response to viral infection. It is located ubiquitously in an inactivated form in the cytoplasm of many immune cells. When phosphorylated it forms a complex with CREBBP to upregulate many immune responses integral to innate immune function.

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