PE anti-human OSMR Antibody, OSMR, S22005H,BioLegend,377108
Clone S22005H does not affect the binding of clone S22005D on target cells.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB199393654
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE anti-human OSMR Antibody, OSMR, S22005H
Cat. No.377108
HostMouse
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberS22005H
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetOSMR
ImmunogenRecombinant human OSMR protein
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Oncostatin M receptor (OSMR), also known as IL-31 receptor subunit beta, is a member of the IL-6 receptor family. It is expressed in bone marrow, endothelium, liver, lung and skin tissues. OSMR forms the type II OSM receptor complex when paired with interleukin 6 signal transducer (gp130) and forms the IL-31 receptor when complexed with interleukin 31 receptor A (IL31RA). The binding of OSM to either of these receptors triggers activation of the JAK-STAT signaling pathway.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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