PE anti-humanmouserat MR1 Antibody, MR1, 8F2F9,BioLegend,396106
This antibody is noted to cross-react to over-expressed mouse, rat, bovine (cow) and human MR11. This clone does not cross-block clone 26.5 based on in-house testing.
Host
Mouse
Reactivity
Human, Mouse, Rat
Application
FC -Quality tested
Platform ID
BAB135835441
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE anti-humanmouserat MR1 Antibody, MR1, 8F2F9
Cat. No.396106
HostMouse
RRIDAB_2814365 (BioLegend Cat. No. 396105)AB_2814366 (BioLegend Cat. No. 396106)
IsotypeMouse IgG1, κ
ReactivityHuman, Mouse, Rat
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number8F2.F9
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetMR1
ImmunogenChimeric mMR1/L molecule (mMR1 [alpha1-alpha2 domain]/Ld [alpha3 cytoplasmic tail]) soluble, recombinant protein secreted by insect cells was used to immunize MR1 KO mice
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
MHC-related protein 1, also known as MR1, is a nonclassical MHC class I molecule highly conserved in mammals, particularly in its α1/α2 domains. MR1 is required for the development and expansion of the mucosal-associated invariant T (MAIT) cells. The transcripts for MR1 are ubiquitously expressed, but its expression on the cell surface seems to be ligand-dependent. MR1 is involved in the presentation of vitamin-derived compounds from bacterial biosynthetic pathways.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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