PE anti-mouse CD132 common gamma chain Antibody anti-CD132 - TUGm2,BioLegend,132305
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB284275420
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE anti-mouse CD132 common gamma chain Antibody anti-CD132 - TUGm2
Cat. No.132305
HostRat
RRIDAB_2123703 (BioLegend Cat. No. 132305)AB_2280163 (BioLegend Cat. No. 132306)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberTUGm2
Concentration0.2 mg/ml
TargetCD132
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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