PE anti-mouse CD144 VE-cadherin Antibody anti-CD144 - BV13,BioLegend,138009

Clone BV13 recognizes an epitope between aa 45 and 56, and has a binding affinity of 5-15 nM5. Additional reported applications (for relevant formats) include: Western blotting1, blocking of cell interactionsin vivo1, and immunofluorescence microscopystaining4.

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB649578841

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePE anti-mouse CD144 VE-cadherin Antibody anti-CD144 - BV13
Cat. No.138009
HostRat
RRIDAB_10639938 (BioLegend Cat. No. 138009)AB_10641139 (BioLegend Cat. No. 138010)
IsotypeRat IgG1, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberBV13
Concentration0.2 mg/ml
TargetCD144
ImmunogenVE-cadherin-Ig fusion protein
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD144, also known as vascular endothelial-cadherin (VE-cadherin), is a 120 kD member of the type II Cadherin family.  It is an endothelial specific hemophilic adhesion molecule involved in endothelial cell survival, migration, contact-dependent growth inhibition, and homophilic adhesion.  VE-cadherin is essential for maintaining the integrity of the endothelial barrierin vivo.

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