PE anti-mouse CD153 Antibody anti-CD153 - RM153,BioLegend,106405
Additional reported applications (for the relevant formats) include: immunoprecipitation, immunohistochemical staining of acetone-fixed frozen sections, andin vivoblocking of CD30 binding to CD30 ligand (CD153)1-3,5. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 106408).
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB835312175

BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NamePE anti-mouse CD153 Antibody anti-CD153 - RM153
Cat. No.106405
HostRat
RRIDAB_2207502 (BioLegend Cat. No. 106405)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberRM153
Concentration0.2 mg/ml
TargetCD153
ImmunogenCHO cells transfected with mouse CD153 gene (Tnfsf8)
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD153 is a 39-40 kD type II membrane glycoprotein, also known as CD30 ligand or CD30L. This TNF superfamily member is expressed on activated T cells. CD153 has been reported to stimulate B-cell proliferation, antigen-specific antibody production, polyclonal immunoglobulin secretion, and T cell activation and proliferation. The RM153 antibody inhibits binding of CD153 to CD30.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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