PE anti-mouse CD184 (CXCR4) Recombinant Antibody anti-CD184 - QA16A08,BioLegend,153806

This recombinant antibody clone is derived from clone L276F12.

Host

Mouse

Reactivity

Mouse

Application

FC -Quality tested

Platform ID

BAB437224498

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePE anti-mouse CD184 (CXCR4) Recombinant Antibody anti-CD184 - QA16A08
Cat. No.153806
HostMouse
RRIDAB_2734225 (BioLegend Cat. No. 153805)AB_2734226 (BioLegend Cat. No. 153806)
IsotypeMouse IgG1, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityRecombinant
Clone NumberQA16A08
Concentration0.2 mg/ml
TargetCD184
ImmunogenMouse CXCR4-transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD184, also known as CXCR4, is a member of the G protein coupled receptor family that binds CXCL12 (SDF1). CXCR4 and CXCL12 play an important role in immune and inflammatory responses through the regulation of cell migration and growth. CXCR4 plays a crucial role in the pathogenesis of several autoimmune diseases such as atherosclerosis, rheumatoid arthritis, and wound healing. In addition, CXCR4 is the cofactor for fusion and entry of the T cell-tropic form of HIV-1.

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