PE anti-mouse CD200R3 Antibody anti-CD200R3 - Ba160,BioLegend,142306

Ba160 recognizes circulating and bone marrow basophils; it also recognizes a subset of mast cells in the peritoneal cavity and skin.A single intravenous administration of 30 µg of LEAF Ba160 to mice induces a dramatic reduction of basophil number in peripheral blood from day 1 to day 10. *Tested in the development stage.

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB270793159

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Product Specifications
Scientific Background

Specifications

NamePE anti-mouse CD200R3 Antibody anti-CD200R3 - Ba160
Cat. No.142306
HostRat
RRIDAB_10917057 (BioLegend Cat. No. 142306)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberBa160
TargetCD200R3
ImmunogenMouse primary basophils
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD200R3, also known as CD200RLb and OX-2 Receptor 3, is a disulfide-linked dimmeric CD200R-like receptor which belongs to immunoglobulin superfamily.  Its positively charged aminio acid lysinein associates with ITAM- or YxxM motif-bearing adaptor molecules such as DAP12, DAP10, FcRγ, and CD3ζ. CD200R3 functions as an activating receptor to regulate IgE independent immune response.

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