PE anti-mouse CD252 OX40L Antibody anti-CD252 - RM134L,BioLegend,108805

The RM134L antibody can block the costimulatory activity of OX40L. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections3, andin vivoandin vitroblocking of OX-40L-OX-40 functional interaction1,2,4. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 108808).

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB460224717

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Product Specifications
Scientific Background

Specifications

NamePE anti-mouse CD252 OX40L Antibody anti-CD252 - RM134L
Cat. No.108805
HostRat
RRIDAB_313404 (BioLegend Cat. No. 108805)AB_313405 (BioLegend Cat. No. 108806)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberRM134L
Concentration0.2 mg/ml
TargetCD252
ImmunogenRat NRK-52E cell line transfected with mouse OX-40L
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD252 is a 35 kD member of the TNF superfamily and is also known as OX40 ligand, OX40L, and CD134L. The CD252 is expressed on activated B cells and antigen presenting cells. CD252 interacts with OX40 antigen (CD134), expressed predominantly on activated T cells to increase proliferation and IL-2 production and to enhance proliferation and immunoglobulin secretion in activated B cells.

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