PE anti-mouse CD255 (TWEAK) Antibody, CD255, A19079J,BioLegend,119105
Host
Mouse
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB114623099
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE anti-mouse CD255 (TWEAK) Antibody, CD255, A19079J
Cat. No.119105
HostMouse
RRIDAB_3106016 (BioLegend Cat. No. 119105)AB_3106016 (BioLegend Cat. No. 119106)
IsotypeMouse IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberA19079J
Concentration0.2 mg/mL
TargetCD255
ImmunogenRecombinant mouse CD255 protein
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD255, also known as TWEAK (TNF-related weak inducer of apoptosis), is a 27 kD protein and a tumor necrosis factor superfamily member 12 (TNFSF12). TWEAK is a type II transmembrane protein expressed on a variety of cell types. A soluble form of TWEAK is produced by proteolytic processing. TWEAK binds to the TWEAK receptor, FN14, to induce apoptosis, NF-κB translocation, and promote angiogenesis and endothelial cell proliferation. It has also been implicated in the induction of inflammatory cytokines.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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