PE anti-mouse CD285 (TLR5) Antibody, CD285, ACT5,BioLegend,148108
Additional reported applications for the relevant formats include: immunoprecipitation of TLR5 from cell lysates1,2.
Host
Mouse
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB703764084
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NamePE anti-mouse CD285 (TLR5) Antibody, CD285, ACT5
Cat. No.148108
HostMouse
RRIDAB_2890696 (BioLegend Cat. No. 148107)AB_2890696 (BioLegend Cat. No. 148108)
IsotypeMouse IgG1, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberACT5
Concentration0.2 mg/mL
TargetCD285
ImmunogenTLR5-transfected Ba/F3 cells
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD285, also known as TLR5, is a 98 kD pattern recognition receptor that binds to bacterial flagellin. It is expressed on dendritic cells, classical monocytes and mucosal epithelial cells and is involved in activation of TLR5 induced NF-κB mediated activation of inflammatory-related target genes. Mutations in the TLR5 gene have been linked with susceptibility to systemic lupus erythematosus and Legionnaire’s disease.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.