PE anti-mouse CD365 Tim-1 Antibody anti-CD365 - RMT1-4,BioLegend,119506

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB898992858

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePE anti-mouse CD365 Tim-1 Antibody anti-CD365 - RMT1-4
Cat. No.119506
HostRat
RRIDAB_2248167 (BioLegend Cat. No. 119505)AB_2232887 (BioLegend Cat. No. 119506)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberRMT1-4
Concentration0.2 mg/ml
TargetCD365
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD365 (Tim-1) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-1 and hepatitis virus cellular receptor 1. It is developmentally expressed at high levels in the blastocyst. Tim-1 is expressed on activated CD4+lymphocytes especially on Th2cells and has been implicated to play a critical role in the development of atopic disease and other Th2-biased immune responses. Tim-1 is hepatitis A virus receptor in humans. Tim-4 is the endogenous ligand of Tim-1. The interaction of Tim-1 and Tim-4 is involved in costimulation of T cell proliferation.  Tim-1 is an endogenous ligand for LMIR5/CD300b.

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