PE anti-mouse GPR15/BOB Antibody anti-GPR15 - S15042I,BioLegend,154603
Host
Rat
Reactivity
Mouse
Application
FC -Quality tested
Platform ID
BAB190797782
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE anti-mouse GPR15/BOB Antibody anti-GPR15 - S15042I
Cat. No.154603
HostRat
RRIDAB_2728214 (BioLegend Cat. No. 154603)AB_2728215 (BioLegend Cat. No. 154604)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberS15042I
Concentration0.2 mg/ml
TargetGPR15/BOB
ImmunogenMouse GPR15-Transfectants
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
GPR15, also known as BOB, is a G-protein coupled receptor with 7 transmembrane regions that is present on the cell surface as a homotrimer. Its ligand, GPR15L, was recently identified. GPR15 is expressed by effector T cells and subsets of memory T cells, and is involved in the recruitment of proinflammatory CD4+T cells responsible of the pathogenesis in colitis. In humans, GPR15 acts as a receptor for human immunodeficiency virus (HIV) type 1 and 2, and is upregulated on monocytes and neutrophils in the synovia of patients with RA.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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