PE anti-mouse PD-1H VISTA Antibody anti-PD-1H - MH5A,BioLegend,143708

Additional reported applications (for the relevant formats) include: inhibition of graft vs host disease (GVHD), Western blotting, and immunohistochemical staining of paraffin embedded tissue sections.

Host

Armenian Hamster

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB315471703

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Product Specifications
Scientific Background

Specifications

NamePE anti-mouse PD-1H VISTA Antibody anti-PD-1H - MH5A
Cat. No.143708
HostArmenian Hamster
RRIDAB_11150600 (BioLegend Cat. No. 143707)AB_11150599 (BioLegend Cat. No. 143708)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberMH5A
Concentration0.2 mg/ml
TargetPD-1H
ImmunogenPD-1H- IgG Fc fusion protein
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

PD-1H, also known as VISTA, is a 309 aa type I transmembrane protein, composed of seven exons. PD-1H has one Ig-V like domain, and its sequence is similar to the Ig-V domains of the members of CD28 and B7 families. PD-1H is expressed by a subset of T cells, macrophages, dendritic cells, neutrophils, and NK cells. It has been proposed that PD-1H can be useful to modulate the host immune response to allogeneic transplants.

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