PE anti-mouse TCR Vγ7 Antibody, TCR Vγ7, F2.67,BioLegend,161705

Host

Mouse

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB284386631

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePE anti-mouse TCR Vγ7 Antibody, TCR Vγ7, F2.67
Cat. No.161705
HostMouse
IsotypeMouse IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberF2.67
Concentration0.2 mg/mL
TargetTCR Vgamma7
ImmunogenMouse hybridoma expressing anti Vγ7Vδ5 TCR
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

T cell receptor (TCR) is a heterodimer consisting of α/β chains (αβ T cells) or γ/δ chains (γδ T cells). γδ T cells are a minor T cell population in the body, with the usage of γ and δ often associated with specific anatomical localization. Vγ7-expressing γδ T cells are resident in the intestinal epithelium and contain a high proportion of extrathymically generated cells. It has been reported that butyrophilin-like molecules Btnl1 with Btnl6 are important in Vγ7+T cell responses.The F2.67 antibody reacts specifically with mouse TCR Vγ7 (as referred to by the Tonegawa nomenclature system for TCR γ and δ chains). Mouse TCR Vγ7 is also known as TCR Vγ5 under the Garman nomenclature system.Several TCR γ and δ chain nomenclature systems exist. In order to consolidate the various nomenclature systems, we have created charts for corresponding names across some of the most popular naming methods.Clickhereto see charts.

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