PE anti-mouse TCR Valpha3.2 [b, c] Antibody anti-TCR V alpha 3.2 - RR3-16,BioLegend,135406

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB838110831

BioLegend

Headquarters

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePE anti-mouse TCR Valpha3.2 [b, c] Antibody anti-TCR V alpha 3.2 - RR3-16
Cat. No.135406
HostRat
RRIDAB_1937256 (BioLegend Cat. No. 135405)AB_1937255 (BioLegend Cat. No. 135406)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberRR3-16
Concentration0.2 mg/ml
TargetTCR Valpha3.2
ImmunogenMouse cytolytic T-cell clone OH6
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

TCR is a heterodimer composed of alpha and beta chains or gamma and delta chains. TCR Vα elements expression is largely independent of MHC haplotype. It is likely that the Vαs interact preferentially with conserved region of class I or class II molecules. RR3-16 antibody reacts with the Vα3.2 T-cell receptor (TCR) of mice having the b (e.g., C57BL/6) and c (e.g.,SJL, NOD) haplotypes, but not with the strains having the a ( Balb/c) or d (DBA/2) haplotype. Vα3.2 TCR is preferentially expressed by CD8+T cells.

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