PE anti-mouse TCR Vbeta12 Antibody anti-TCR V beta 12 - MR11-1,BioLegend,139703
Host
Mouse
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB497906621
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE anti-mouse TCR Vbeta12 Antibody anti-TCR V beta 12 - MR11-1
Cat. No.139703
HostMouse
RRIDAB_10643999 (BioLegend Cat. No. 139703)AB_10639729 (BioLegend Cat. No. 139704)
IsotypeMouse IgG1, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberMR11-1
Concentration0.2 mg/ml
TargetTCR Vbeta12
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
T cell receptor Vβ12 (TCR Vβ12) is a variant of TCR β chain and, along with TCR α chain, forms the TCR heterodimer. In association with the CD3 complex, TCR α/β is responsible for antigen recognition through interaction with MHC-peptide complex to initiate the T cell-mediated immune responses. The MR11-1 antibody reacts with the Vβ12 TCR of mice bearing thebhaplotype. It has been reported that Mtv-8 and Mtv-9 cause clonally deletion of Vβ12+ T cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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