PE anti-mouse TCR Vbeta7 Antibody anti-TCR V beta 7 - TR310,BioLegend,118308

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Additional reported applications (for the relevant formats) include immunoprecipitation2.

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB970169941

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePE anti-mouse TCR Vbeta7 Antibody anti-TCR V beta 7 - TR310
Cat. No.118308
HostRat
RRIDAB_893631 (BioLegend Cat. No. 118307)AB_893628 (BioLegend Cat. No. 118308)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberTR310
Concentration0.2 mg/ml
TargetTCR Vbeta7
ImmunogenT cell lymphoma TK-1
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

The TR310 antibody reacts with the mouse T cell receptor Vβ7 segment . T cells expressing the α/β T cell receptor use clonally distributed TCRs to recognize cell-bound antigens such as peptide/MHC complexes and viral superantigens. The α/β TCR is an oligomeric TCR complex composed of covalently bound α and β chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3δ, γ, ε, and ζ chains. The TR310 antibody reacts with one such clonally distributed TCR β chain known as Vβ7. Vβ7 is expressed on a small subpopulation of both CD4+and CD8+T cells. The TR310 antibody has been used for the identification of Vβ7 expressing T cells by flow cytometry and immunoprecipitation.

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