PE anti-mouse TCR Vgamma3 Antibody anti-TCR V gamma 3 - 536,BioLegend,137503

Additional reported (for relevant formats) application include: immunoprecipitation1and immunofluorescence2.This product may be used for research purposes only. It is not licensed for resale and may only be used by the buyer. This product may not be used and is not licensed for clinical assays, where the results of such assays are provided as a diagnostic service. If a diagnostic or therapeutic use is anticipated, then a license must be requested from the University of California. This availability of such diagnostic and therapeutic use license(s) cannot be guaranteed from the University of California.

Host

Syrian Hamster

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB064758310

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePE anti-mouse TCR Vgamma3 Antibody anti-TCR V gamma 3 - 536
Cat. No.137503
HostSyrian Hamster
RRIDAB_10551420 (BioLegend Cat. No. 137503)AB_10550807 (BioLegend Cat. No. 137504)
IsotypeSyrian Hamster IgG
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number536
Concentration0.2 mg/ml
TargetTCR Vgamma3
ImmunogenAKR mouse dendritic epidermal cell clone 7-17
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Vγ3+T cells are the predominant γδ TCR-bearing cells in early fetal thymus. The majority of CD3+cells in 14-day fetal thymus express Vγ3. Vγ3 is also expressed on Thy-1+dendritic epidermal cells (Thy-1+DECs). Cells that express Vγ3 are not significantly detectable in adult lymphoid organs. It has been reported that Lck and Fyn, two Src family kinases, are required for the development of Vγ3+T cells.Clone 536 reacts with the Vγ3 segment as designated by the Garman nomenclature system. Mouse TCR Vγ3 is also known as TCR Vγ5 under the Heilig & Tonegawa nomenclature system.Several TCR γ and δ chain nomenclature systems exist. In order to consolidate the various nomenclature systems, we have created charts for corresponding names across some of the most popular naming methods.Clickhereto see charts.

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.