PE anti-mouse Tim-2 Antibody anti-Tim-2 - F37-2C4,BioLegend,129006
Host
Mouse
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB346967842
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePE anti-mouse Tim-2 Antibody anti-Tim-2 - F37-2C4
Cat. No.129006
HostMouse
RRIDAB_1227792 (BioLegend Cat. No. 129006)
IsotypeMouse IgG1, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberF37-2C4
Concentration0.2 mg/ml
TargetTim-2
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Tim-2 is a transmembrane protein known as T cell immunoglobulin and mucin domain containing protein-2. It is expressed on activated T cells and preferentially on differentiated Th2cells. Sema4A is the ligand of Tim-2. A blockade of Tim-2/Tim-2 ligand interaction results in T cell hyperproliferation and Th2cytokine production. Tim-2 plays a critical role in the development of atopic disease and other Th2-biased immune responses.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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