PE anti-mouse alpha-GalCer:CD1d complex Antibody anti-alpha-GalCer-CD1d complex - L363,BioLegend,140506
Additional reported applications (for the relevant formats) include: Surface and intracellular immunofluorescence2and block a-GalCer:mCD1d1 complex induced iNKT activation1.
Host
Mouse
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB619182174
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NamePE anti-mouse alpha-GalCer:CD1d complex Antibody anti-alpha-GalCer-CD1d complex - L363
Cat. No.140506
HostMouse
RRIDAB_10645470 (BioLegend Cat. No. 140505)AB_10642814 (BioLegend Cat. No. 140506)
IsotypeMouse IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberL363
Concentration0.2 mg/ml
Immunogenα-GalCer:mCD1d1 complexes coupled to Mycobacterium tuberculosis PPD
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
The L363 antibody reacts with α-GalCer:mouse CD1d complex. Glycolipid α-galactosylceramide (α-GalCer) is a potent activator of human and murineiNKT cells and is widely used as a model antigen for the studies ofiNKT-mediated immunity. The glycolipid binds to CD1d and forms a complex which is subsequently recognized byiNKT cells, a subset of T cells expressing invariant TCR α chain Vα14, analogous to the peptide-MHC complex recognition by TCR α/ß T cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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