PE anti-mouse/human CD207 Langerin Antibody anti-CD207 - 4C7,BioLegend,144204

Host

Mouse

Reactivity

Mouse, Human

Application

FC - Quality testedIHC - Verified

Platform ID

BAB186122556

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePE anti-mouse/human CD207 Langerin Antibody anti-CD207 - 4C7
Cat. No.144204
HostMouse
RRIDAB_2561498 (BioLegend Cat. No. 144203)AB_2561499 (BioLegend Cat. No. 144204)
IsotypeMouse IgG2a, κ
ReactivityMouse, Human
ApplicationFC - Quality testedIHC - Verified
ClonalityMonoclonal
Clone Number4C7
Concentration0.2 mg/ml
TargetCD207
ImmunogenLangerin extracellular domain-Fc fusion protein
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD207, also known as langerin, is a 40 kD single-pass type II transmembrane protein, member of the C-type lectin family. CD207 is expressed on the cell surface and Birbeck granules (BGs) of Langerhans cells, and subsets of thymic and splenic dendritic cells. Its ligands are mannose,n-acetylglucosamine, fucose, and sulfated glycans. Langerin is involved in the antigen processing pathway through capture and internalization of its ligands.

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