PE anti-rat CD152 Antibody anti-CD152 - WKH203,BioLegend,203007

Additional reported applications (for the relevant formats) include: immunoprecipitation1.

Host

Mouse

Reactivity

Rat

Application

ICFC - Quality tested

Platform ID

BAB476416941

BioLegend

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Contact

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Product Specifications
Scientific Background

Specifications

NamePE anti-rat CD152 Antibody anti-CD152 - WKH203
Cat. No.203007
HostMouse
RRIDAB_2276898 (BioLegend Cat. No. 203007)
IsotypeMouse IgG1, κ
ReactivityRat
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone NumberWKH203
Concentration0.2 mg/ml
TargetCD152
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD152 is a 33 kD member of the immunoglobulin superfamily also known as CTLA-4 or Ly-56. It is expressed on activated T and B lymphocytes. CD152 is similar to CD28 in amino acid sequence, structure, and genomic organization and these two receptors share common B7 family counter-receptors (B7-1, B7-2). Whereas CD28 delivers a costimulatory signal in T cell activation, CTLA-4 negatively regulates cell-mediated immune responses. CD152 is thought to play a role in the induction and maintenance of immunological tolerance, as well as the development of protective immunity and thymocyte regulation.

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