PE anti-rat CD25 Antibody anti-CD25 - OX-39,BioLegend,202105
Additional reported applications (for the relevant formats) include: immunohistochemistryof acetone-fixed frozen sections1, immunoprecipitation1, weakly blocks IL-2 binding1, 2, 3, and blocks IL-2 induced epithelial cell migration3.
Host
Mouse
Reactivity
Rat
Application
FC - Quality tested
Platform ID
BAB325366951
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NamePE anti-rat CD25 Antibody anti-CD25 - OX-39
Cat. No.202105
HostMouse
RRIDAB_314002 (BioLegend Cat. No. 202105)
IsotypeMouse IgG1, κ
ReactivityRat
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberOX-39
Concentration0.2 mg/ml
TargetCD25
ImmunogenRat T cell blasts from mixed lymphocyte reactions
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD25 is a 55 kD glycoprotein also known as IL-2 receptor α chain. It is broadly expressed on activated T and B cells, a subset of thymic and splenic dendritic cells, and intestinal epithelial cells in the rat. IL-2 is a critical cytokine involved in lymphocyte proliferation and clonal expansion. IL-2 signaling requires the high affinity IL-2 receptor composed of IL-2 receptor chains α, β, and γ. The OX-39 antibody weakly inhibits IL-2 binding to the IL-2 receptor and has been shown to block some IL-2 mediated responsesin vitro.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.