PE anti-rat CD314 (NKG2D) Antibody, CD314 (NKG2D), 11D5C9,BioLegend,206303

Host

Mouse

Reactivity

Rat

Application

FC - Quality tested

Platform ID

BAB914108128

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePE anti-rat CD314 (NKG2D) Antibody, CD314 (NKG2D), 11D5C9
Cat. No.206303
HostMouse
RRIDAB_2890732 (BioLegend Cat. No. 206303)AB_2890732 (BioLegend Cat. No. 206304)
IsotypeMouse IgG1, κ
ReactivityRat
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number11D5C9
Concentration0.2 mg/mL
TargetCD314
ImmunogenRat NKG2D fused with human Fc
PurityThe antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

NKG2D is a lectin-like type II transmembrane protein also known as CD314. It is expressed on NK cells and a subset of T lymphocytes. NKG2D serves as a stimulatory receptor to activate NK cells via the non-covalently associated DAP10 or DAP12 adaptor. Rat NKG2D has been reported to induce the synthesis of IFN gamma and induce cytotoxicity in response to rat RAE1L and PRLT, RAE family members in rat. NKG2D is also involved in liver allograft rejection.

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