PE anti-rat IL-4 Antibody anti-IL-4 - OX-81,BioLegend,511906

Host

Mouse

Reactivity

Rat

Application

ICFC - Quality tested

Platform ID

BAB888397946

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePE anti-rat IL-4 Antibody anti-IL-4 - OX-81
Cat. No.511906
HostMouse
RRIDAB_2128984 (BioLegend Cat. No. 511905)AB_2128983 (BioLegend Cat. No. 511906)
IsotypeMouse IgG1, κ
ReactivityRat
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone NumberOX-81
Concentration0.2 mg/ml
TargetIL-4
ImmunogenRecombinant rat IL-4
PurityThe antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells and basophils. IL-4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of naïve CD4+T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10 and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells

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