PEDazzle 594 anti-human IL-6 Antibody, IL-6, MQ2-13A5,BioLegend,501122

ELISA or ELISPOT Capture1-3,7:The purified MQ2-13A5 antibody is useful as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated MQ2-39C3 antibody (Cat. No. 501202) as the detecting antibody.Neutralization1-3,5,6:The Ultra-LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for neutralization of human IL-6 bioactivity (Cat. No. 501110). The MQ2-13A5 antibody can neutralize the bioactivity of natural or recombinant IL-6.Additional applications (for the relevant formats) include:intracellular flow cytometry10.

Host

Rat

Reactivity

Human

Application

ICFC -Quality tested

Platform ID

BAB882500778

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePEDazzle 594 anti-human IL-6 Antibody, IL-6, MQ2-13A5
Cat. No.501122
HostRat
RRIDAB_2810621 (BioLegend Cat. No. 501121)AB_2810622 (BioLegend Cat. No. 501122)
IsotypeRat IgG1, κ
ReactivityHuman
ApplicationICFC -Quality tested
ClonalityMonoclonal
Clone NumberMQ2-13A5
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetIL-6
ImmunogenCOS-7- expressed, recombinant human IL-6
PurityThe antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survival of certain B cells and T cells. IL-6 plays a role in host defense, acute phase reactions, immune response, and hematopoiesis. IL-6 is expressed by T cells, B cells, monocytes, fibroblasts, hepatocytes, endothelial cells, and keratinocytes.

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