PERK Antibody (YA233),MedChemexpress,HY-P80781

PERK Antibody (YA233) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PERK.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB

Conjugate

Non-conjugated

Platform ID

BAB000693215

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

1 Deer Park Drive, Suite FMONMOUTH JUNCTION, NI 08852, USA

MedChemexpress

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Email:

[email protected]

Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NamePERK Antibody (YA233)
Cat. No.HY-P80781
Accession NumberQ9NZJ5
Gene ID (Entrez)9451
HostRabbit
RRIDAB_3095844
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB
Working DilutionsWB: 1:500-1:1000
ClonalityRecombinant,Monoclonal
Clone NumberYA233
Molecular WeightPredicted band size: 125 kDa; Observed band size: 140 kDa
ImmunogenSynthetic peptide corresponding to Human PERK.The exact sequence is proprietary to MCE.
Purityaffinity purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

PERK: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]

Synonyms

EIF2AK3; PEK; PERK; Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; HsPEK

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