PERK Rabbit pAb- ABclonal,ABclonal,A25172
Reactivity
Human, Mouse
Application
IF/ICC, ELISA
Conjugate
Unconjugated
Platform ID
BAB863476121
ABclonal
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Product Specifications
Scientific Background
Specifications
NamePERK Rabbit pAb- ABclonal
Cat. No.A25172
RRID#N/A
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationIF/ICC, ELISA
Working DilutionsIF/ICC:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular WeightRefer to figures
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only
Scientific Background
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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