PGCD antibody,Genetex,GTX14786

Host

Rabbit

Reactivity

Human, Mouse, Rat, Baboon

Application

WB ICC/IF IHC-P IP ELISA

Conjugate

Unconjugated

Platform ID

BAB602235370

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePGCD antibody
Cat. No.GTX14786
Gene ID (Entrez)3000
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Baboon
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IP ELISA
ClonalityPolyclonal
Concentration0.75-1.20 mg/ml (Please refer to the vial label for the specific concentration.)
TargetG
ImmunogenSynthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase D protein.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationTris/Glycine, 0.5% BSA, 30% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq, Dec 2008]

Synonyms

guanylate cyclase 2D, retinal , CACD1 , CORD5 , CORD6 , CYGD , GUC1A4 , GUC2D , LCA , LCA1 , RCD2 , RETGC-1 , ROS-GC1 , ROSGC , retGC

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