PGHS-2 Rabbit pAb- ABclonal,ABclonal,A24438

Reactivity

Human

Application

WB

Conjugate

Unconjugated

Platform ID

BAB744610675

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

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Product Specifications
Scientific Background

Specifications

NamePGHS-2 Rabbit pAb- ABclonal
Cat. No.A24438
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB
Working DilutionsWB:1:500 - 1:1000
Molecular Weight70kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

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