PHD2 antibody,Genetex,GTX82966
Host
Rabbit
Reactivity
Human, Mouse, Rat
Application
WB ICC/IF IHC-P IP
Conjugate
Unconjugated
Platform ID
BAB378575192
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Product Specifications
Scientific Background
Synonyms
Specifications
NamePHD2 antibody
Cat. No.GTX82966
Gene ID (Entrez)112405
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IP
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetEgln1
ImmunogenA synthetic peptide made to an internal portion of mouse PHD2/HIF Prolyl Hydroxylase 2 (between residues 300-400). [UniProt# Q91YE3]
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only
Scientific Background
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
Synonyms
egl-9 family hypoxia-inducible factor 1 , AI503754 , C1orf12 , HIF-PH2 , HPH-2 , Hif-p4h-2 , ORF13 , Phd2 , SM-20
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.