PIK3R1 Monoclonal Antibody, AbBy Fluor-680 Conjugated,Bioss,bsm-52219m-bf680-100ul

Host

Mouse

Reactivity

Human, Mouse, Rat

Application

WB, IF

Conjugate

AbBy Fluor-680

Platform ID

BAB960516875

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePIK3R1 Monoclonal Antibody, AbBy Fluor-680 Conjugated
Cat. No.bsm-52219m-bf680-100ul
Accession NumberP27986
Gene ID (Entrez)5295
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Rat
ConjugationAbBy Fluor-680
ApplicationWB, IF
Working DilutionsWB:1:300-5000 | IF:
ClonalityMonoclonal
Concentration1ug/ul
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Synonyms

Phosphatidylinositol 3-kinase regulatory subunit alpha; PIK3R1; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PIK3R1; GRB1; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha

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