PKR/EIF2AK2 Rabbit mAb,ABclonal,A19545
Reactivity
Human
Application
WB, IF/ICC, ELISA
Conjugate
Unconjugated
Platform ID
BAB725731006
ABclonal
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Product Specifications
Scientific Background
Synonyms
Specifications
NamePKR/EIF2AK2 Rabbit mAb
Cat. No.A19545
Accession NumberP19525
Gene ID (Entrez)5610
RRIDAB_2862660
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IF/ICC, ELISA
Working DilutionsWB:1:1000 - 1:4000 | IF/ICC:1:50 - 1:100 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC0024
Molecular Weight70 kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only
Scientific Background
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses.
Synonyms
PKR; PRKR; DYT33; LEUDEN; EIF2AK1; PPP1R83; PKR/EIF2AK2
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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