PML Recombinant Antibody,Bioss,bsm-61469r

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF

Conjugate

Unconjugated

Platform ID

BAB930420064

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePML Recombinant Antibody
Cat. No.bsm-61469r
Accession NumberP29590
Gene ID (Entrez)5371
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF
Working DilutionsWB:1:300-5000 | IHC-P:1:200-400 | IHC-F:1:100-500 | IP:1-2ug | IF: | Flow-Cyt:1ug/Test | ICC/IF:1:50-100
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Regulates RB1 phosphorylation and activity. Required for normal development of the brain cortex during embryogenesis. Can sequester herpes virus and varicella virus proteins inside PML bodies, and thereby inhibit the formation of infectious viral particles. Regulates phosphorylation of ITPR3 and plays a role in the regulation of calcium homeostasis at the endoplasmic reticulum. Regulates transcription activity of ELF4.

Synonyms

Protein PML; Promyelocytic leukemia protein; RING finger protein 71; Tripartite motif-containing protein 19; MYL; PP8675; RNF71; TRIM19.

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