PNPase antibody [3H5],Genetex,GTX70199

Host

Mouse

Reactivity

Human

Application

ICC/IF

Conjugate

Unconjugated

Platform ID

BAB547028089

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePNPase antibody [3H5]
Cat. No.GTX70199
Gene ID (Entrez)87178
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationICC/IF
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPNPT1
ImmunogenThe immunogen used to generate this antibody corresponds to human PNPase.
PurityAffinity purified by Protein G.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene belongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. This enzyme is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7. [provided by RefSeq, Dec 2012]

Synonyms

polyribonucleotide nucleotidyltransferase 1 , COXPD13 , DFNB70 , OLD35 , PNPASE , old-35

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