POLG Antibody (YA2783),MedChemexpress,HY-P83038

POLG Antibody (YA2783) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to POLG.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB

Conjugate

Non-conjugated

Platform ID

BAB142447669

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

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Contact

Tel: 609-228-6898
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Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NamePOLG Antibody (YA2783)
Cat. No.HY-P83038
Accession NumberP54098
Gene ID (Entrez)5428
HostRabbit
RRIDAB_3105154
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB
Working DilutionsWB: 1:500-1:1000
ClonalityRecombinant,Monoclonal
Clone NumberYA2783
Molecular WeightPredicted band size: 140 kDa; Observed band size: 140 kDa
ImmunogenA synthesized peptide derived from human DNA Polymerase gamma
PurityAffinity Purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by The related gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in The related gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for The related gene.

Synonyms

MDP1; PEO; PolG alpha; POLG; POLG1; POLGA; SANDO; SCAE

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