POLR1B Rabbit pAb- ABclonal,ABclonal,A12034

Reactivity

Human, Mouse

Application

WB, ELISA

Conjugate

Unconjugated

Platform ID

BAB230967227

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NamePOLR1B Rabbit pAb- ABclonal
Cat. No.A12034
RRID#N/A
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB, ELISA
Working DilutionsWB:1:500 - 1:2000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight128kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).

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