PON3 Rabbit pAb- ABclonal,ABclonal,A16418

Reactivity

Human

Application

WB, ELISA

Conjugate

Unconjugated

Platform ID

BAB101207013

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NamePON3 Rabbit pAb- ABclonal
Cat. No.A16418
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, ELISA
Working DilutionsWB:1:500 - 1:2000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight39kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized.

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