PORCN Rabbit pAb- ABclonal,ABclonal,A12250

Reactivity

Mouse, Rat

Application

WB, ELISA

Conjugate

Unconjugated

Platform ID

BAB107404037

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NamePORCN Rabbit pAb- ABclonal
Cat. No.A12250
RRID#N/A
IsotypeIgG
ReactivityMouse, Rat
ConjugationUnconjugated
ApplicationWB, ELISA
Working DilutionsWB:1:500 - 1:1000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight52kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the porcupine family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Disruption of this gene is associated with focal dermal hypoplasia, and the encoded protein has been implicated in cancer. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

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