POT1 antibody,Genetex,GTX30601

Host

Rabbit

Reactivity

Human, Primate

Application

WB

Conjugate

Unconjugated

Platform ID

BAB873250278

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePOT1 antibody
Cat. No.GTX30601
Gene ID (Entrez)25913
HostRabbit
IsotypeIgG
ReactivityHuman, Primate
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration2.25 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPOT1
ImmunogenA synthetic peptide made to an internal portion of the human POT1 protein sequence (between residues 200-300). [UniProt# Q9NUX5]
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationTris-Glycine, 150mM NaCl,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq]

Synonyms

protection of telomeres 1 , CMM10 , GLM9 , HPOT1

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