PR/SET Domain 14 (PRDM14) Antibody,Abbexa,abx026617

Similar to acetylation and phosphorylation, histone methylation at the N terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET domain containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET domain family, and another 17 make up the PR domain family that is related to the SET domain family. PRDM14 is part of a family of PR domain genes that are involved in tumorigenesis. It may function as a transcription factor.

Host

Rabbit

Reactivity

Human

Application

ELISA, WB, IHC, IF/ICC

Conjugate

Unconjugated

Platform ID

BAB205293580

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NamePR/SET Domain 14 (PRDM14) Antibody
Cat. No.abx026617
Accession NumberQ9GZV8
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB, IHC, IF/ICC
Working DilutionsWB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 64.1 kDa
ImmunogenKLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PRDM14.
PurityPurified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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