PRAME antibody,Genetex,GTX03709
Host
Rabbit
Reactivity
Human, Mouse
Application
WB
Conjugate
Unconjugated
Platform ID
BAB223460947
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
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Product Specifications
Scientific Background
Synonyms
Specifications
NamePRAME antibody
Cat. No.GTX03709
Gene ID (Entrez)23532
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPRAME
ImmunogenA synthesized peptide derived from human PRAME(Accession P78395), corresponding to amino acid residues W481-C505.
PurityPurified by antigen-affinity chromatographyFrom serum
Appearance/FormLiquid
FormulationPBS, 150mM NaCl, 50% Glycerol,0.02% sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only
Scientific Background
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Synonyms
preferentially expressed antigen in melanoma , CT130 , MAPE , OIP-4 , OIP4
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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